ROUNDWORMS IN HUMANS
We normally do not think of human roundworm infection as a problem in the modern world but in fact it is. Studies have surveyed playground soil samples across the U.S. and found up to 20% of samples to be contaminated with roundworm eggs. Antibody testing shows approximately 14% of the U.S. population at large to have been infected by a roundworm species. Most infections occur in people under age 20 with children being at highest risk.
Most people have very mild or no symptoms but it all depends on how many worm eggs one is exposed to. The worms of concern are Toxocara canis and Toxocara felis. These species of roundworms employ a full body migration through their host as part of their development, and symptoms in the human host result as a part of this migration. Three syndromes are described:
COVERT TOXOCARIASIS - Variable symptoms occur as the worm larvae make their way through the human body: fever, abdominal discomfort, swollen lymph nodes, cough, headache, sleep disturbances. This is the mildest of the three syndromes.
VISCERAL LARVA MIGRANS - This syndrome is basically a more intense version of the above and happens when large numbers of larvae are migrating (same symptoms but more severe since more larvae are involved). After larvae are finished with their migration or have gotten lost in the process, symptoms usually subside in a few weeks but human death has occurred from visceral larva migrans in severe cases. Most visceral larva migrans patients are young children (age 1-4) as they are ones who are at highest risk from oral exposure to contaminated soil.
OCULAR LARVA MIGRANS - When roundworm larvae migrate in their natural host (dog, cat), the larvae are able to recognize molecular "signposts" directing them on their proper route so that they end up in the GI tract at the end of their journey, having undergone the proper development along the way. In the human body, however, the signposts are all wrong and the larvae tend to get lost. They die or are killed by the host immune system during their journey. For unknown reasons, roundworm larvae are frequently misdirected to the human eye where they die and generate tremendous inflammation. Usually one eye and one single larva are involved. Vision loss occurs over days to weeks and permanent blindness can result. Damage to the eye is permanent. Children age 7-8 are typically infected.
Approximately 1000 cases of Ocular Larva Migrans are seen in the U.S. annually
HOW DOES THIS HAPPEN?
The most significant thing you can do to prevent this infection is to wash your hands before cooking and eating and teach your children to do the same.
Keep children from putting dirty objects in their mouths whenever possible.
Regularly deworm pets according to the Roundworm recommendations at the Companion Animal Parasite Control website.
For more information on this human infection with Roundworms, please visit one of the Center for Disease Control Web sites on Visceral Larva Migrans at:
Page last updated: 1/22/2021