(for veterinary information only)
BRAND NAMES: MARQUIS, PONALRESTAT
Ponazuril represents a new approach to treatment. Ponazuril actually kills the coccidia which makes for a faster response to treatment and shorter course of therapy. The problem for dogs and cats is that ponazuril is manufactured for horses and comes in paste that is impractical for small animal use. The paste can be diluted and used orally in dogs and cats for control of coccidia. It is common for animal shelters and other areas where coccidia are common to automatically treat puppies and kittens and intake
For more information on coccidia click here.
HOW THIS MEDICATION IS USED
For intestinal coccidia, the compounded formula is given orally for 1 - 7 days. A three day course seems to be the most common recommendation.
For Toxoplasmosis or to treat infection with Neospora caninum (both conditions being special more invasive coccidia infections), ponazuril should be given approximately one month.
Horses sometimes get an upset stomach or even a rash around the mouth where the medication is delivered. (In horses, ponazuril is often given for 28 days as their target parasite requires a longer course). So far this medication has not been formally studied in small animals despite its wide use in shelter situations.
There have been reports of reduced ability to produce tears (keratoconjunctivitis sicca) in dogs, particularly in breeds that have a predisposition to having tear function problems.
CONCERNS AND CAUTIONS
Page posted: 8/24/2008