Methocarbamol

(for veterinary information only)

BRAND NAME: ROBAXIN-V

AVAILABLE IN   
500 mg TABLETS  
(AND INJECTABLE)

USES OF THIS MEDICATION

Methocarbamol is a muscle relaxant that exerts its effect by acting on the central nervous system (i.e. the nerves of the brain and spinal cord that control the muscles) rather than on the muscles themselves. Methocarbamol can be used in any condition where painful muscle spasms should be reduced for patient comfort (intervertebral disc disease, for example) but it is also considered the treatment of choice for metaldehyde (snail bait) poisoning, a condition causing severe muscle twitching. Methocarbamol is also used in the treatment of tetanus (which is characterized by muscle rigidity) and strichnine poisoning (characterized by stiffness and seizuring). In cats, methocarbamol is an important medication in the treatment of permethrin poisoning (which occurs when canine permethrin flea products are used inadvertently on pet cats.)

An oral dose of methocarbamol is active in the body approximately 30 minutes after administration with activity peaking in 2 hours (in humans).

SIDE EFFECTS

In addition to being a muscle relaxant, methobarbamol also has some sedative properties. Sensitive animals will salivate or vomit.

One might notice that the patientís urine is darker than normal on methocarbamol but this is not cause for concern.

INTERACTIONS WITH OTHER MEDICATIONS

The sedative side effect is exaggerated when methocarbamol is given with other medications that have sedating properties.

Dogs with myasthenia gravis receiving pyridostigmine may experience extreme weakness if these two drugs are combined.

CONCERNS AND CAUTIONS

Methocarbamol has not been fully tested for safety in pregnancy.

Page last reviewed: 2/20/2012